Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.8
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium (as ZumXR® magnesium oxide, magnesium citrate)
250 mg
60%
Top Medical Research Studies
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
Most Useful Reviews
9
Potent relief
2 people found this helpful
This magnesium quality is remarkably potent. The benefits are quite strong for me, but if you require it, it will undoubtedly assist with sleep, bones, joints, and muscle pain.
Read More
9
Eliminated hip pain
2 people found this helpful
I've experienced soft pains in my hips and left leg for eleven years after giving birth. While it didn't prevent my daily activities, it was uncomfortable, particularly in cold weather. I started taking this two years ago and have had no pain since. I truly believe in its effectiveness!
Read More
9
Joint pain reduction
2 people found this helpful
I gave this to my father, who was suffering from knee and joint pain overall. He noticed a difference from the first week, especially combined with other supplements like boron, trace minerals, magnesium oil, and collagen. This combination significantly reduces joint pain, muscle pain, and enhances sleep and general health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
- All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Potent relief
2 people found this helpful
This magnesium quality is remarkably potent. The benefits are quite strong for me, but if you require it, it will undoubtedly assist with sleep, bones, joints, and muscle pain.
Read More
9
Eliminated hip pain
2 people found this helpful
I've experienced soft pains in my hips and left leg for eleven years after giving birth. While it didn't prevent my daily activities, it was uncomfortable, particularly in cold weather. I started taking this two years ago and have had no pain since. I truly believe in its effectiveness!
Read More
9
Joint pain reduction
2 people found this helpful
I gave this to my father, who was suffering from knee and joint pain overall. He noticed a difference from the first week, especially combined with other supplements like boron, trace minerals, magnesium oil, and collagen. This combination significantly reduces joint pain, muscle pain, and enhances sleep and general health.
Read More
7.5
Overall wellness
Life Extension's Extended-Release Magnesium is a well-crafted supplement that promotes muscle function, heart health, and overall wellness. Its extended-release technology provides consistent magnesium benefits throughout the day. It's essential for muscle relaxation, energy production, and bone health. Many users report feeling more relaxed and experiencing fewer muscle cramps with improved energy levels. Overall, this is an excellent choice for those seeking a high-quality supplement for better health.
Read More
7.5
Soothing effect
86 people found this helpful
I liked it and found it comfortable. I have a shoulder pain. I take it before bed, and it calms the pain and relaxes me.
Read More
Frequently Asked Questions
9
Joint pain reduction
2 people found this helpful
I gave this to my father, who was suffering from knee and joint pain overall. He noticed a difference from the first week, especially combined with other supplements like boron, trace minerals, magnesium oil, and collagen. This combination significantly reduces joint pain, muscle pain, and enhances sleep and general health.
9
Eliminated hip pain
2 people found this helpful
I've experienced soft pains in my hips and left leg for eleven years after giving birth. While it didn't prevent my daily activities, it was uncomfortable, particularly in cold weather. I started taking this two years ago and have had no pain since. I truly believe in its effectiveness!
7.5
Pain reduction
6 people found this helpful
I ordered it for the second time, previously purchasing a 100 pill package. I noticed that my period pain has subsided, possibly due to the magnesium, and it has improved my sleep greatly, allowing me to sleep deeply. It also alleviates constipation and relaxes my muscles considerably. I recommend taking it regularly, ideally before bedtime. The pill size is good.
6
Bone health support
1 people found this helpful
Magnesium serves multiple purposes. It promotes bone health, heart health, fights inflammation, and helps with stress relief. It relaxes muscles, easing tension in the shoulders and neck. This magnesium includes both quick release and extended release forms to optimise absorption. I take one capsule with meals.
6
Digestive aid
1 people found this helpful
After experiencing constipation from a high-calcium supplement, I used magnesium for relief, which also softens my stool. It's helpful for post-workout muscle pain and sleep. However, results can vary; my husband sometimes experiences diarrhoea when taking it.
6
Effective relief
5 people found this helpful
I specifically bought this magnesium with prolonged release for sudden pain instead of NSAIDs. My husband was undergoing dental prosthetics, which caused discomfort. I started giving him this magnesium – one pill for mild pain, two for stronger pain. Although the relief isn't immediate, it gradually subsides, making it better than traditional painkillers. This product is harmless with pure magnesium, and my family's sleep has improved, waking up refreshed. It's become essential for us, with 60 tablets in a jar for a reasonable price.
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
References
- Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. 10.3389/fbioe.2023.1153969
- Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
- Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
